SKIL Antibody - Cat. #: CSB-PA932063

SKU: CSB-PA932063

Size :50ul

Clone Number:

Aliases:OTTHUMP00000213557 antibody; OTTHUMP00000213591 antibody; OTTHUMP00000213592 antibody; OTTHUMP00000213595 antibody; SKI like antibody; SKI like oncogene antibody; Ski like protein antibody; SKI like proto oncogene antibody; Ski related oncogene antibody; Ski related oncogene snoN antibody; Ski related protein antibody; Ski-like protein antibody; Ski-related oncogene antibody; Ski-related protein antibody; SKIL antibody; SKIL_HUMAN antibody; SNO antibody; SnoA antibody; SnoI antibody; SnoN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P12757

Immunogen:Fusion protein of Human SKIL

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:30-1:150

Background:The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SKIL

Research Areas:Epigenetics and Nuclear Signaling;Cancer