SHB Antibody - Cat. #: CSB-PA125145

SKU: CSB-PA125145

Size :100ul

Clone Number:

Aliases:bA3J10.2 antibody; OTTHUMP00000021397 antibody; RP11 3J10.8 antibody; RP113J10.8 antibody; SH2 domain containing adapter protein B antibody; SH2 domain-containing adapter protein B antibody; SHB (Src homology 2 domain containing) adaptor protein B antibody; SHB adaptor protein (a Src homology 2 protein) antibody; SHB adaptor protein antibody; Shb antibody; SHB_HUMAN antibody; Src homology 2 domain containing adaptor protein B antibody; Src homology 2 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15464

Immunogen:Synthesized peptide derived from C-terminal of Human SHB.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Welsh M., Oncogene 9:19-27(1994).
Humphray S.J., Nature 429:369-374(2004).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SHB

Research Areas:Developmental biology;Signal transduction?Stem cells