SGMS2 Antibody, FITC conjugated - Cat. #: CSB-PA854159LC01HU

SKU: CSB-PA854159LC01HU

Size :50ug

Clone Number:

Aliases:MGC26963 antibody; Phosphatidylcholine:ceramide cholinephosphotransferase 2 antibody; SGMS 2 antibody; Sgms2 antibody; SM synthase antibody; SMS 2 antibody; SMS2 antibody; SMS2_HUMAN antibody; Sphingomyelin synthase 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8NHU3

Immunogen:Recombinant Human Phosphatidylcholine:ceramide cholinephosphotransferase 2 protein (1-79AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SGMS2

Research Areas:Cancer; Metabolism; Signal transduction