SF3B1 Antibody - Cat. #: CSB-PA021125LA01HU

SKU: CSB-PA021125LA01HU

Size :50ug

Clone Number:

Aliases:Hsh155 antibody; OTTHUMP00000205700 antibody; OTTHUMP00000205702 antibody; OTTHUMP00000225001 antibody; OTTHUMP00000225002 antibody; Pre mRNA processing 10 antibody; Pre mRNA splicing factor SF3b, 155 kDa subunit antibody; Pre-mRNA splicing factor SF3b 155 kDa subunit antibody; Pre-mRNA-splicing factor SF3b 155 kDa subunit antibody; PRP10 antibody; PRPF10 antibody; SAP 155 antibody; SAP155 antibody; sf3b1 antibody; SF3B1_HUMAN antibody; SF3b155 antibody; Spliceosome associated protein 155 antibody; Spliceosome-associated protein 155 antibody; Splicing factor 3B subunit 1 antibody; Splicing factor 3b, subunit 1, 155kDa antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75533

Immunogen:Recombinant Human Splicing factor 3B subunit 1 protein (186-378AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500

Background:Subunit of the splicing factor SF3B required for \\\'A\\\' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the \\\'E\\\' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SF3B1

Research Areas:Epigenetics and Nuclear Signaling