SETD7 Antibody - Cat. #: CSB-PA093769

SKU: CSB-PA093769

Size :50ul

Clone Number:

Aliases:FLJ21193 antibody; H3 K4 HMTase antibody; H3-K4-HMTase SETD7 antibody; H4 lysine 4 specific antibody; Histone H3 K4 methyltransferase antibody; Histone H3 lysine 4 specific methyltransferase antibody; Histone H3-K4 methyltransferase SETD7 antibody; Histone H4 K4 methyltransferase antibody; Histone lysine N methyltransferase antibody; Histone lysine N methyltransferase H3 lysine 4 specific SET7 antibody; Histone-lysine N-methyltransferase SETD7 antibody; KIAA1717 antibody; KMT7 antibody; Lysine methyltransferase antibody; Lysine N-methyltransferase 7 antibody; OTTHUMP00000164543 antibody; OTTHUMP00000220049 antibody; SET 7 antibody; SET 7/9 antibody; SET 9 antibody; SET D7 antibody; SET domain containing (lysine methyltransferase) 7 antibody; SET domain containing protein 7 antibody; SET domain containing protein 8 antibody; SET domain-containing protein 7 antibody; SET7 antibody; SET7/9 antibody; SET9 antibody; Setd7 antibody; SETD7_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8WTS6

Immunogen:Fusion protein of Human SETD7

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:The methylation of histones plays a pivotal role in the regulation of chromatin structure and gene expression. Histone methylation can occur on Arg or Lys residues, with an exquisite site selectivity for Lys methylation at specific positions in the N-termini of histones H3 and H4. SET7/9, a histone methyltransferase (HMTase), which transfers methyl groups to Lys4 of histone H3, forms a complex with S-adenosyl-L-methionine. This complex contains an active site consisting of a binding pocket where an AdoMet molecule in an unusual conformation binds, a narrow substrate-specific channel that only unmethylated lysine residues can access and a catalytic tyrosine residue.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SETD7

Research Areas:Epigenetics and Nuclear Signaling