SEMA5A Antibody, FITC conjugated - Cat. #: CSB-PA613413LC01HU

SKU: CSB-PA613413LC01HU

Size :50ug

Clone Number:

Aliases:SEMA5A antibody; SEMAF antibody; Semaphorin-5A antibody; Semaphorin-F antibody; Sema F antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13591

Immunogen:Recombinant Human Semaphorin-5A protein (201-400AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SEMA5A

Research Areas:Others