SELH Rabbit Polyclonal Antibody

SKU: BT-AP04690

Size:100μL

Background:This gene encodes a nucleolar protein| which belongs to the SelWTH family. It functions as an oxidoreductase| and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways| promote mitochondrial biogenesis and mitochondrial function| and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein| containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon| which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure| designated the Sec insertion sequence (SECIS) element| that is necessary for the recognition of UGA as a Sec codon| rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.

Research_area:Epigenetics and nuclear signaling

Target_protein:SELH

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:SELH

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):13420

UniProt accession:Human: Q8IZQ5; Mouse: Q3UQA7

Synonyms:SELH

GeneID:Human: 280636; Mouse: 72657