SDHB Polyclonal Antibody

SKU: E-AB-16795

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SDHB

Target Synonym: CWS2;DHSB;FLJ92337;Ip;Iron sulfur subunit;Iron sulfur subunit of complex II;Iron-sulfur subunit of complex II;mitochondrial;PGL 4;PGL4;SDH 1;SDH;SDH1;SDH2;SDH2;homolog of;SdhB;SDHIP;Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial;Succinate dehydrogenase [ubiquinone] iron sulfur subunit;Succinate dehydrogenase [ubiquinone] iron-sulfur subunit;succinate dehydrogenase [ubiquinone] iron-sulfur subunit;mitochondrial;Succinate Dehydrogenase 1 Iron Sulfur Subunit;Succinate Dehydrogenase 2;S. cerevisiae;homolog of;Succinate dehydrogenase complex iron sulfur subunit B;Succinate dehydrogenase complex subunit B iron sulfur;Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein;succinate dehydrogenase complex;subunit B;iron sulfur (Ip);Succinate dehydrogenase iron sulfur protein

Research Areas: Cancer;Cell biology;Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P21912

Accession:

Background: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human SDHB

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 32kDa

ObservedMW: