SCN11A Polyclonal Antibody

SKU: E-AB-16054

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SCN11A

Target Synonym: hNaN;NaN;NAV1.9;Peripheral nerve sodium channel 5;PN 5;PN5;SCN 11A;SCN 12A;Scn11a;SCN12A;SCNBA;Sensory neuron sodium channel 2;SNS 2;SNS2;Sodium channel protein type 11 subunit alpha;Sodium channel protein type XI subunit alpha;Sodium channel voltage gated type XI alpha;Sodium channel voltage gated type XI alpha polypeptide;Sodium channel voltage gated type XI alpha subunit;Sodium channel voltage gated type XII alpha polypeptide;Voltage gated sodium channel Nav1.9;Voltage gated sodium channel subunit alpha Nav1.9;Voltage-gated sodium channel subunit alpha Nav1.9

Research Areas: Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9UI33

Accession:

Background: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human SCN11A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: