S100B Polyclonal Antibody

SKU: D-AB-10368L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:S100B

Target Synonym:NEF;Protein S100 B;Protein S100-B;S 100 calcium binding protein beta chain;S 100 protein beta chain;S-100 protein beta chain;S-100 protein subunit beta;S100;S100 calcium binding protein beta (neural);S100 calcium-binding protein B;S100 protein beta chain;S100B;S100B;S100beta

Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Stem cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P04631

Accession:

Background:S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system (CNS), S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new bomarker for mood disorders.

Concentration:1 mg/mL

Immunogen:Recombinant Human S100B protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:IHC 1:2000-1:4700

Calculated MW:

ObservedMW: