S100B Antibody - Cat. #: CSB-PA074357

SKU: CSB-PA074357

Size :50ul

Clone Number:

Aliases:NEF antibody; Protein S100 B antibody; Protein S100-B antibody; S 100 calcium binding protein beta chain antibody; S 100 protein beta chain antibody; S-100 protein beta chain antibody; S-100 protein subunit beta antibody; S100 antibody; S100 calcium binding protein beta (neural) antibody; S100 calcium-binding protein B antibody; S100 protein beta chain antibody; S100B antibody; S100B_HUMAN antibody; S100beta antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P04271

Immunogen:Synthetic peptide of Human S100B

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:S100B

Research Areas:Epigenetics and Nuclear Signaling;Cell biology;Stem cells