S Antibody, HRP conjugated - Cat. #: CSB-PA336163EB01HIY

SKU: CSB-PA336163EB01HIY

Size :50ug

Clone Number:

Aliases:S antibody; 3Spike glycoprotein antibody; S glycoprotein antibody; E2 antibody; Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2'] antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human) coronavirus OC43

UniProt ID:P36334

Immunogen:Recombinant Human coronavirus OC43 Spike glycoprotein protein (15-344AA)

Raised in:Rabbit

Species Reactivity:Human coronavirus OC43

Tested Applications:ELISA

Background:S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection. S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:S

Research Areas:Others