RUNX3 Monoclonal Antibody

SKU: BT-MCA3161

Size:100μL

Background:This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:RUNX3

applications:IHC, ICC, FCM

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:2B3

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:RUNX3

Immunogen:Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):44.4kDa

UniProt accession:Q13761

Synonyms:AML2, CBFA3, PEBP2aC, FLJ34510, MGC16070

GeneID:864