RTEL1 Antibody, FITC conjugated - Cat. #: CSB-PA020563LC01HU

SKU: CSB-PA020563LC01HU

Size :50ug

Clone Number:

Aliases:RTEL1 antibody; C20orf41 antibody; KIAA1088 antibody; NHLRegulator of telomere elongation helicase 1 antibody; EC 3.6.4.12 antibody; Novel helicase-like antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NZ71

Immunogen:Recombinant Human Regulator of telomere elongation helicase 1 protein (975-1219AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RTEL1

Research Areas:Epigenetics and Nuclear Signaling