RPUSD4 Antibody, Biotin conjugated - Cat. #: CSB-PA836192LD01HU

SKU: CSB-PA836192LD01HU

Size :50ug

Clone Number:

Aliases:RNA pseudouridylate synthase domain-containing protein 4 antibody; rpusd4 antibody; RUSD4_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96CM3

Immunogen:Recombinant Human Mitochondrial RNA pseudouridine synthase RPUSD4 protein (41-240AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome (PubMed:27974379). Acts on position 39 in mitochondrial tRNA(Phe) (PubMed:28082677). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RPUSD4

Research Areas:Others