RPE65 Antibody, FITC conjugated - Cat. #: CSB-PA624103LC01HU

SKU: CSB-PA624103LC01HU

Size :50ug

Clone Number:

Aliases:All-trans-retinyl-palmitate hydrolase antibody; LCA 2 antibody; LCA2 antibody; Leber congenital amaurosis antibody; mRPE 65 antibody; mRPE65 antibody; p63 antibody; rd 12 antibody; rd12 antibody; Retinal pigment epithelium specific 61 kDa protein antibody; Retinal pigment epithelium specific 65 kDa protein antibody; Retinal pigment epithelium specific protein antibody; Retinal pigment epithelium specific protein 65kDa antibody; Retinal pigment epithelium-specific 65 kDa protein antibody; Retinitis pigmentosa 20 antibody; Retinoid isomerohydrolase antibody; Retinol isomerase antibody; RP 20 antibody; RP20 antibody; RPE 65 antibody; RPE65 antibody; RPE65_HUMAN antibody; sRPE 65 antibody; sRPE65 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q16518

Immunogen:Recombinant Human Retinoid isomerohydrolase protein (348-484AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RPE65

Research Areas:Neuroscience; Cancer; Tags & Cell Markers; Metabolism; Signal transduction