RNF40 Antibody, Biotin conjugated - Cat. #: CSB-PA019890LD01HU

SKU: CSB-PA019890LD01HU

Size :50ug

Clone Number:

Aliases:95 kDa retinoblastoma associated protein antibody; 95 kDa retinoblastoma protein binding protein antibody; 95 kDa retinoblastoma-associated protein antibody; BRE 1B antibody; BRE1 B antibody; BRE1 E3 ubiquitin ligase homolog B antibody; BRE1-B antibody; BRE1B antibody; BRE1B_HUMAN antibody; DKFZp686K191 antibody; E3 ubiquitin protein ligase BRE1B antibody; E3 ubiquitin-protein ligase BRE1B antibody; KIAA0661 antibody; MGC13051 antibody; Rb associated protein antibody; RBP 95 antibody; RBP95 antibody; RING finger protein 40 antibody; Ring finger protein 40 E3 ubiquitin protein ligase antibody; RNF 40 antibody; Rnf40 antibody; STARING antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75150

Immunogen:Recombinant Human E3 ubiquitin-protein ligase BRE1B protein (471-724AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of \'Lys-120\' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 \'Lys-4\' and \'Lys-79\' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RNF40

Research Areas:Cell biology