RNF139 Antibody - Cat. #: CSB-PA788709

SKU: CSB-PA788709

Size :50ul

Clone Number:

Aliases:RNF139 antibody; TRC8 antibody; E3 ubiquitin-protein ligase RNF139 antibody; EC 2.3.2.27 antibody; RING finger protein 139 antibody; RING-type E3 ubiquitin transferase RNF139 antibody; Translocation in renal carcinoma on chromosome 8 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8WU17

Immunogen:Synthetic peptide of Human RNF139

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RNF139

Research Areas:Cancer;Cell biology