RIP3(Phospho-Ser227) Rabbit Polyclonal Antibody

SKU: BT-AP12295

Size:100μL

Background:The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases| and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm| and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex| and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Research_area:Cancer; Cell biology; Immunology; Signal transduction

Target_protein:RIPK3

applications:WB

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:RIP3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9Y572; Mouse: Q9QZL0; Rat: Q9Z2P5

Synonyms:RIP3 ;Ser227 ; Receptor-interacting serine/threonine-protein kinase 3; EC 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3

GeneID:Human: 11035; Rat: 246240