RHOB Polyclonal Antibody

SKU: E-AB-12248

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:RHOB

Target Synonym:Aplysia RAS-related homolog 6;ARH6;ARHB;H6;MST081;MSTP081;oncogene RHO H6;ras homolog family member B;ras homolog gene family;member B;Rho cDNA clone 6;Rho related GTP binding protein RhoB Precursor;Rho-related GTP-binding protein RhoB;Rhob;RHOB;RHOH6

Research Areas:Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P62745

Accession:

Background:Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Concentration:0.4 mg/mL

Immunogen:Synthetic peptide of human RHOB

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:1000-1:2000

Calculated MW:22kDa

ObservedMW: