RFIP5 Polyclonal Antibody

SKU: BT-AP13683

Size:100μL

Background:disease:Antibodies against RIP11 are found in sera from patients with systemic lupus erythematosus (SLE) or Sjoegren syndrome (SS), and in the sera from mothers of children with neonatal lupus erythematosus (NLE).,Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by Mg(2+) rather than Ca(2+).,Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane.,PTM:Phosphorylated on serine and threonine residues.,Contains 1 C2 domain.,subunit:Forms an heterooligomeric complex with RAB11FIP4. Binds NAPG and SSA2. Binds RAB11A that has been activated by GTP binding.,tissue specificity:Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.,

Research_area:Metabolism; Signal transduction; Tags & cell markers

Target_protein:RAB11FIP5

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Rab11 family-interacting protein 5

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9BXF6; Mouse: Q8R361

Synonyms:Rab11 family-interacting protein 5 ;Rab11-FIP5;Gamma-SNAP-associated factor 1;Gaf-1;Phosphoprotein pp75;Rab11-interacting protein Rip11

GeneID:Human: 26056