RELN antibody , Cat. # FNab07235

SKU: FNab07235

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation(By similarity).

Immunogen:reelin

Synonyms:

Observed MW:62 kDa

Uniprot ID:P78509

Reactivity:Human

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:20-1:200

Gene ID:5649

Research Area:Neuroscience, Metabolism, Developmental biology