RECQ5 rabbit pAb

SKU: ES13430

Size: 100μL

Source:Rabbit

Applications:WB;ELISA;IHC

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

Immunogen:Synthesized peptide derived from human RECQ5 AA range: 647-697

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:9400

Human_swiss_prot_no:O94762

Subcellular_location:[Isoform Beta]: Nucleus, nucleoplasm . Nucleus . Recruited to sites of DNA damage, such as single-strand breaks and inter-strand cross-links, and at stalled replication forks. Re-localizes from the nucleolus into the nucleus after replicative stress and significantly associates with WRN during S-phase (PubMed:23180761). .; [Isoform Alpha]: Cytoplasm .; [Isoform Gamma]: Cytoplasm .

Other_name:

Background:The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],