Recombinant XIAP Monoclonal Antibody

SKU: AN300702L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:XIAP

Target Synonym:ILP;XLP;API;BIRC;Inhibitor of apoptosis protein;Baculoviral IAP repeat-containing protein;IAP;XIAP;API3;BIRC4;IAP-3;ILP1;MIHA;XLP2;hIAP-3;hIAP3;X-linked inhibitor of apoptosis;Baculoviral IAP repeat-containing protein 4;E3 ubiquitin-protein ligase XIAP;IAP-like protein;Inhibitor of apoptosis protein 3;RING-type E3 ubiquitin transferase XIAP;X-linked inhibitor of apoptosis protein;IAP3

Research Areas:Cell Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11D11

UNIProt ID:P98170

Accession:

Background:This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human XIAP protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:57 kDa

ObservedMW:57 kDa