Recombinant Vinculin Monoclonal Antibody

SKU: AN300693L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Vinculin

Target Synonym:CMH;HEL;Epididymis luminal protein;CMD1W;CMH15;Epididymis luminal protein 114;HEL114;Metavinculin;MV;MVCL;OTTHUMP00000019861;OTTHUMP00000019862;VINC;Vinculin;VCL;Mvinculin

Research Areas:Signal Transduction;Cardiovascular;Isotype;Loading Controls

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:10F9

UNIProt ID:P18206

Accession:

Background:Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Vinculin protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:124 kDa

ObservedMW:124 kDa