Recombinant TLS/FUS Monoclonal Antibody

SKU: AN301003L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:TLS

Target Synonym:ETM;ALS;POMP;HNRNPP;FUS;ALS6;ETM4;FUS1;HNRNPP2;POMP75;TLS;RNA-binding protein FUS;ALS6;ETM4;FUS1;HNRNPP2;POMP75;RNA-binding protein FUS;TLS;16) in malignant liposarcoma);16) malignant liposarcoma;75 kDa DNA pairing protein;75 kDa DNA-pairing protein;Amyotrophic lateral sclerosis 6;FUS CHOP;Fus like protein;Fused in sarcoma;Fusion (involved in t(12;Fusion derived from t(12;Fusion gene in myxoid liposarcoma;Heterogeneous nuclear ribonucleoprotein P2;hnRNP P2;Oncogene FUS;Oncogene TLS;RNA binding protein FUS;TLS CHOP;Translocated in liposarcoma;Translocated in liposarcoma protein

Research Areas:Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:12B9

UNIProt ID:P35637

Accession:

Background:This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human TLS/FUS protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:500-1:2000;WB 1:500-1:2000

Calculated MW:53 kDa

ObservedMW:70 kDa