Recombinant Thyroglobulin Monoclonal Antibody

SKU: AN301675L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Thyroglobulin

Target Synonym:TDH;TG;AITD3;TGN;AITD 3;hTG;TDH3;THYG;Thyroglobulin;AITD 3;AITD3;hTG;TDH3;Tg;TGN;THYG;Thyroglobulin

Research Areas:Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:IHC;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A378

UNIProt ID:P01266

Accession:

Background:Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules.

Concentration:1 mg/mL

Immunogen:Recombinant human Thyroglobulin fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:IHC 1:100-1:1000;FCM 1:50-1:100

Calculated MW:

ObservedMW: