Recombinant STAT6 Monoclonal Antibody

SKU: AN300728L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Stat6

Target Synonym:D12S;STAT;Signal Transducer and Activator of Transcription;D12S1644;IL-4-STAT;STAT6B;STAT6C;STAT6;IL-4 Stat;Signal Transducer and Activator of Transcription 6;12S1644;IL 4 STAT;IL4 STAT;Interleukin 4 Induced;Interleukin 4 Induced Transcription Factor IL4 STAT;interleukin4 induced;Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced;Signal Transducer And Activator Of Transcription 6 Nirs Variant 1;STAT 6;STAT interleukin4 induced;Transcription factor IL 4 STAT

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Kits;Lysates;Other

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6H1

UNIProt ID:P42226

Accession:

Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human STAT6 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:94 kDa

ObservedMW:110 kDa