Recombinant SMARCA2/BRM Monoclonal Antibody

SKU: AN301908L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:SMARCA2/BRM

Target Synonym:SNF2L;SMARCA;BAF190B;BRM;SNF2A;SNF2L2;SMARCA2;ATP dependent helicase SMARCA2;ATP-dependent helicase SMARCA2;BAF190;BRG1-associated factor 190B;FLJ36757;Global transcription activator homologous sequence;hBRM;hSNF2a;MGC74511;Possible global transcription activator SNF2L2;Probable global transcription activator SNF2L2;Protein brahma homolog;SMCA2;SNF2 alpha;SNF2 like 2;SNF2/SWI2 like protein 2;SNF2-alpha;SNF2LA;Sth1p;Sucrose nonfermenting 2 like protein 2;SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A624

UNIProt ID:P51531

Accession:

Background:SMARCA2, also named as BRM, is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 is involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

Concentration:1 mg/mL

Immunogen:Recombinant human SMARCA2/BRM fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000;IHC 1:500-1:3000

Calculated MW:181 kDa

ObservedMW:220 kDa