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GeneBio Systems

Recombinant SH-PTP2 Monoclonal Antibody

Recombinant SH-PTP2 Monoclonal Antibody

SKU:AN300806L

Regular price $434.24 CAD
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:SH-PTP2

Target Synonym:SHP;PTN;SAP;BPTP;PTPN;BPTP3;CFC;JMML;METCDS;NS1;PTP-1D;PTP2C;SH-PTP2;SH-PTP3;SHP2;PTPN11;PTN11;SAP2;SHPTP3;Syp;SHPTP2;MGC14433;OTTHUMP00000166107;OTTHUMP00000166108;Protein tyrosine phosphatase 2;Protein tyrosine phosphatase 2C;Protein tyrosine phosphatase non receptor type 11;Protein-tyrosine phosphatase 1D;Protein-tyrosine phosphatase 2C;PTP1D;PTP2-C;PTP-2C;SH2 domain containing protein tyrosine phosphatase 2;SHP 2;SHP-2;Syp;Tyrosine-protein phosphatase non-receptor type 11

Research Areas:Signal Transduction;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4B5

UNIProt ID:Q06124

Accession:

Background:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human SH-PTP2 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:68 kDa

ObservedMW:68 kDa

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