Recombinant SARS-CoV-2 Spike RBD protein (His Tag)

SKU: CD00015

Size:1 mg

Background:SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.

Research_area:Others

Purity:>95%（by SDS-PAGE）

Source:E.coli

Full product name:Recombinant SARS-CoV-2 Spike RBD protein, His Tag

Biological activity:

Synonyms:

Endotoxin:<5.0 EU/ug

Storage:-80ºC

Sequence:

uniprot accession:PDTC2

Molecular weight:Approximately 25 kDa

Formulation:

Reconstitution: