Recombinant Rhesus macaque IL-33/Interleukin-33 Protein (His Tag)

SKU: PKSQ050072

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Cytokines

Abbreviation: IL-33;Interleukin-33

Target Synonym: DVS;NF-HEV and IL- 1F;Interleukin-1 family member;C9orf;C9orf26;DVS27;Interleukin-1 family member 11;NF-HEV and IL- 1F11;NKHEV;IL33;Interleukin-33;IL-33;Interleukin 33;IL1F11;NFEHEV;NF-HEV

Research Areas:

Conjugation:

Target Species: Rhesus macaque

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: F7DLG4

Accession: F7DLG4

Background: Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

Concentration:

Activity: Not validated for activity

Sequence: Ser112-Ile270

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 20.3 kDa

ObservedMW: 21 kDa