Recombinant Rat CXCL3 Protein(Trx Tag)

SKU: PDER100111

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:CXCL3

Target Synonym:C-X-C motif chemokine 3;C-X-C motif chemokine ligand 3;Chemokine (C X C motif) ligand 3;Chemokine (CXC motif) ligand 3;Cinc 2;CINC 2b;Cinc2;CINC2b;CXCL 3;Cxcl3;CXCL3;Cytokine induced neutrophil chemoattractant 2;Dcip1;Dendritic cell inflammatory protein 1;Gm1960;GRO protein gamma;GRO-gamma;GRO-gamma(1-73);GRO-gamma(5-73);GRO3;GRO3 oncogene;GROG;Growth regulated protein gamma;Growth-regulated protein gamma;Macrophage inflammatory protein 2 beta precursor;Macrophage inflammatory protein 2-beta;Melanoma growth stimulatory activity gamma;Member 3;MGSA gamma;MIP 2b;MIP2-beta;MIP2B;SCYB3;Small inducible cytokine subfamily B

Research Areas:Immunology

Conjugation:

Target Species:Rat

Expression Host:E.coli

Application:

Fusion tag:N-Trx

UNIProt ID:Q10746

Accession:Q10746

Background:CXCL3 is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3 autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. CXCL3 and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.

Concentration:

Activity:Not validated for activity

Sequence:Arg33-Ser101

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:27.6 kDa

ObservedMW:30 kDa