Recombinant PRMT7 Monoclonal Antibody

SKU: E-AB-81600

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:PRMT7

Target Synonym:[Myelin basic protein]-arginine N-methyltransferase PRMT7;ANM7;FLJ10640;Histone-arginine N-methyltransferase PRMT7;KIAA1933;Myelin basic protein arginine N methyltransferase;OTTHUMP00000174863;PRMT7;Protein arginine methyltransferase 7;Protein arginine N-methyltransferase 7

Research Areas:Cancer;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R06-4F6

UNIProt ID:Q9NVM4

Accession:

Background:Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).

Concentration:300 μg/mL

Immunogen:A synthetic peptide of human PRMT7

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:500-1:2000

Calculated MW:79kDa

ObservedMW:79kDa