Recombinant Phospho-VEGF Receptor 2 (Tyr1175) Monoclonal Antibody

SKU: AN300385L

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:KDR

Target Synonym:Krd;VEGF Receptor;Fetal liver kinase;Protein-tyrosine kinase receptor flk;Vascular endothelial growth factor receptor;sVEGFR;VEGF R;6130401C;FLK;CD309;FLK1;VEGFR;VEGFR2;VEGF Receptor 2;KDR;6130401C07;Fetal liver kinase 1;FLK-1;Kinase insert domain receptor;Krd-1;Ly73;Protein-tyrosine kinase receptor flk-1;sVEGFR-2;Vascular endothelial growth factor receptor 2;VEGF R2;VEGFR-2;KDR

Research Areas:Cardiovascular;Microbiology;Signal Transduction;Stem Cells;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Monoclonal

Clone NO.:11G9

UNIProt ID:P35968

Accession:

Background:Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Concentration:1 mg/mL

Immunogen:A synthetic peptide corresponding to the residues around Tyr1175 of Human Phospho-VEGF Receptor 2

Buffer:10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Purification method:Protein A

Dilution:WB 1:1000-1:10000

Calculated MW:152 kDa

ObservedMW:280 kDa