Recombinant Phospho-PLCγ1 (Tyr783) Monoclonal Antibody

SKU: AN301390L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:PLCγ1

Target Synonym:PLCG;phospholipase C gamma;NCKAP;PLCgamma;PLC;PLCG1;NCKAP3;PLC-II;PLC1;PLC148;PLCgamma1;phospholipase C gamma 1;NCKAP3;phospholipase C gamma 1;PLC1;PLC148;PLCgamma1;PLC-II;PLCG1

Research Areas:Cardiovascular;Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11A1

UNIProt ID:P19174

Accession:

Background:The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Tyr783) of Human Phospho-PLCγ1

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:149 kDa

ObservedMW:149 kDa