Recombinant Phospho-p70 S6 Kinase 1 (Thr389) Monoclonal Antibody

SKU: AN300363P

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:RPS6KB1

Target Synonym:RPS6KB;S6K-beta;PS6K;S6K;S6K-beta-1;S6K1;STK14A;p70 S6KA;p70(S6K)-alpha;p70-S6K;p70-alpha;P70 S6K;RPS6KB1;p70S6KA;70 kDa ribosomal protein S6 kinase 1;alpha 1;alpha 2;KS6B1;p70 alpha;P70 beta 1;p70 ribosomal S6 kinase alpha;p70 ribosomal S6 kinase beta 1;P70 S6 Kinase;p70 S6 kinase alpha;p70 S6K-alpha;p70(S6K) alpha;P70S6K;p70-S6K 1;P70S6K1;p70S6Kb;Ribosomal protein S6 kinase 70kDa polypeptide 1;Ribosomal protein S6 kinase beta 1;Ribosomal protein S6 kinase beta-1;Ribosomal protein S6 kinase I;Serine/threonine kinase 14 alpha;Serine/threonine-protein kinase 14A

Research Areas:Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Monoclonal

Clone NO.:12G12

UNIProt ID:P23443

Accession:

Background:This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Concentration:1 mg/mL

Immunogen:A synthetic phosphopeptide corresponding to residues around Thr389 of human p70 S6 kinase 1.

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:1000-1:200000

Calculated MW:59 kDa

ObservedMW:60 kDa,80 kDa