Recombinant Phospho-Acetyl-CoA Carboxylase (Ser79) Monoclonal Antibody

SKU: AN301391L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Acetyl-CoA Carboxylase

Target Synonym:ACACA;ACAC;ACACAD;ACC;ACC1;ACCA;ACC

Research Areas:Cardiovascular;Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11A2

UNIProt ID:Q13085;O00763

Accession:

Background:Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Ser79) of Human Phospho-Acetyl-CoA Carboxylase

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:1000-1:15000

Calculated MW:266 kDa

ObservedMW:266 kDa