Recombinant PGC1 β Monoclonal Antibody

SKU: AN300994L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:PGC1 β

Target Synonym:PGC;PPARGC;6-pyruvoyl tetrahydrobiopterin synthase;PTP synthase;PTPS;PTS;PERC;PGC1;PGC1B;PPARGC1;PPARGC1B;coactivator 1;coactivator 1 beta;gamma;peroxisome proliferative activated receptor;peroxisome proliferator-activated receptor gamma;peroxisome proliferator-activated receptor gamma coactivator 1 beta;Peroxisome proliferator-activated receptor gamma coactivator 1-beta;PGC-1(beta);PGC-1-beta;PGC-1-related estrogen receptor alpha coactivator;PPAR gamma coactivator-1beta;PPAR-gamma coactivator 1-beta;PPARGC-1-beta;PRGC2

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11B11

UNIProt ID:Q86YN6

Accession:

Background:The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human PGC1 β protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000;

Calculated MW:113 kDa

ObservedMW:113 kDa