Recombinant Pandinus impeRator Pandinin-2

Recombinant Pandinus impeRator Pandinin-2

CSB-YP306050PAU
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Size: 200ug. Other sizes are also available. Please Inquire.

In Stock: No

Lead time: 22-32 working days

Research Topic: Others

Uniprot ID: P83240

Gene Names: N/A

Organism: Pandinus imperator (Emperor scorpion)

AA Sequence: FWGALAKGALKLIPSLFSSFSKKD

Expression Region: 1-24aa

Sequence Info: Full Length

Source: Yeast

Tag Info: N-terminal 6xHis-tagged

MW: 4.6 kDa

Alternative Name(s): Non-disulfide-bridged peptide 3.1 Short name: NDBP-3.1 Non-disulfide-bridged peptide 4.1 Short name: NDBP-4.1

Relevance: Disrupts cell membranes through formation of pores. Has strong antimicrobial activity against Gram-positive bacteria B.subtilis, S.epidermidis, E.faecalis and S.aureus. Is less active against Gram-negative bacteria P.aeruginosa and E.coli. Also increases efficacy of antibiotics (ampicillin, chloramphenicol, streptomycin, kanamycin, novobiocin) when tested against E.coli, probably by facilitating their incorporation into the bacteria. Possesses antifungal activity against C.albicans and hemolytic activity against human, sheep and pig erythrocytes.

Reference: "Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator."Corzo G., Escoubas P., Villegas E., Barnham K.J., He W., Norton R.S., Nakajima T.Biochem. J. 359:35-45(2001)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage Buffer: Tris-based buffer,50% glycerol

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

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