Recombinant Nibrin Monoclonal Antibody

SKU: AN301138L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Nibrin

Target Synonym:MGC;Cell cycle regulatory protein p;Nijmegen breakage syndrome protein;NBN;AT-V1;AT-V2;ATV;NBS;NBS1;P95;nibrin;AT V1;AT V2;Cell cycle regulatory protein p95;FLJ10155;MGC87362;NBS 1;Nijmegen breakage syndrome;Nijmegen breakage syndrome 1 (nibrin);Nijmegen breakage syndrome protein 1;p95 protein of the MRE11/RAD50 complex;ATV;AT-V1;AT-V2;NBS;NBS1;nibrin;P95;Nibrin

Research Areas:Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11A8

UNIProt ID:O60934

Accession:

Background:Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Nibrin protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:2000-1:10000

Calculated MW:85 kDa

ObservedMW:95 kDa