Recombinant Neurofilament heavy polypeptide Monoclonal Antibody

SKU: AN301031L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Neurofilament heavy polypeptide

Target Synonym:KIAA;CMT2CC;NFH;NEFH;NF H;NF-H;200 kDa neurofilament protein;Neurofilament heavy polypeptide;Neurofilament heavy polypeptide 200kDa;Neurofilament triplet H protein;KIAA0845;Heavy Polypeptide 200kDa;Neurofilament;Neurofilament Heavy;NF-H

Research Areas:Neuroscience;Signal Transduction;Stem Cells;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5A6

UNIProt ID:P12036

Accession:

Background:Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Neurofilament heavy polypeptide protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:1000-1:5000

Calculated MW:110 kDa

ObservedMW:180-200 kDa