Recombinant MSH6/GTBP Monoclonal Antibody

SKU: AN300176P

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:MSH6

Target Synonym:MSH;mutS homolog;HNPCC;MSH6;GTBP;GTMBP;HNPCC5;HSAP;p160;mutS homolog 6;GTBP;GTMBP;HNPCC5;HSAP;mutS homolog 6;p160

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Cynomolgus;Mouse;Rat;Ferret

Application:IHC-P;ICC/IF

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:8B1

UNIProt ID:P52701

Accession:

Background:This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.

Concentration:1 mg/mL

Immunogen:A synthetic peptide corresponding to the center region of the Human MSH6 / GTBP

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;ICC/IF 1:20-1:100;

Calculated MW:

ObservedMW: