Recombinant Mouse MIP-3 Beta/CCL19 protein

SKU: CD00293

Size:5 ug

Background:CCL19, also known as EBI1 Ligands chemokine (ELC) and macrophage inflammatory protein-3-beta, is encoded by the CCL19 gene which is located on chromosome 4 in mouse. The protein is expressed at high levels in thymus and lymph nodes, with intermediate levels in trachea and colon and low levels in stomach, lung and some other organs. CCL19 is signal through CCR7 and chemotaxis of T and B lymphocytes and myeloid progenitor cells.

Research_area:Immunology

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Mouse Macrophage Inflammatory Protein-3 beta/CCL19

Biological activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human mature dendritic cells is in a concentration range of 1-1 ng/ml.

Synonyms:MIP-3β/CCL19, CKb11, ELC, MIP-3b, MIP3B, SCYA19,Mouse

Endotoxin:Less than 1 EU/μg of rMuMIP-3β/CCL19 as determined by LAL method.

Storage:-20ºC

Sequence:GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS

uniprot accession:O746; Q8R17

Molecular weight:Approximately 9.2 kDa, a single non-glycosylated polypeptide chain containing 83 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4.