Recombinant Mouse MIG/CXCL9 protein

SKU: CD00299

Size:5 ug

Background:CXCL9 belongs to the CXC chemokine family and also known as Monokine induced by gamma interferon (MIG). It is a T-cell chemoattractant induced by IFN-γ. CXCL9 is closely related to two other CXC chemokines called CXCL10 and CXCL11, additionally they all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3. It is a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response and chemotactic for activated T-cells. Recombinant Mouse CXCL9 contains 105 amino acids which is a single non-glycosylated polypeptide chain. Furthermore, The Mouse CXCL9 shares 75 % and 88 % a.a. sequence identity with human and rat CXCL9.

Research_area:Immunology

Purity:> 95 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Mouse Monokine Induced by Interferon-gamma/CXCL9

Biological activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of .1-1. ng/ml.

Synonyms:MIG/CXCL9, BB13992, CMK, Mi, Mig, MuMIG, Scyb, Scyb9, crg-1, crg-1,Mouse

Endotoxin:Less than 1 EU/μg of rMuMIG/CXCL9 as determined by LAL method.

Storage:-20ºC

Sequence:TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT

uniprot accession:P1834

Molecular weight:Approximately 12.2 kDa, a single non-glycosylated polypeptide chain containing 15 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 × PBS, pH 7.4.