Recombinant Mouse Fas Ligand/TNFSF6 Protein(Fc Tag)

SKU: PDMM100156

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:Fas Ligand/TNFSF6

Target Synonym:Tnfsf;Apt1lg;IL-27p;IL-27;ALPS1B;APTL;CD178;IL;IL27-A;IL-27-A;IL-27p28;Apt1lg1;Cd95l;Fasl;gld;Tnfsf6;Faslg;Fas; CD95L; APO-1; TNFSF6; TNFRSF6;CD95L;IL-

Research Areas:

Conjugation:

Target Species:Mouse

Expression Host:Mammalian

Application:

Fusion tag:C-Fc

UNIProt ID:P41047

Accession:P41047

Background:Fas Ligand , also known as FASLG and CD95L , is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance , in the antigen-stimulated suicide of mature T-cells , or both.

Concentration:

Activity:Not validated for activity

Sequence:Pro132-Leu279

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:41.2 kDa

ObservedMW:55-60 kDa