Recombinant MMP2 Monoclonal Antibody

SKU: AN300712L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:MMP2

Target Synonym:TBE;CLG;Matrix Metalloproteinase;MMP;CLG4;CLG4A;MMP-2;MMP-II;MONA;TBE-1;MMP2;72 kDa Gelatinase;72 kDa Type IV Collagenase;Gelatinase A;Matrix Metalloproteinase-2;72kD type IV collagenase;72kDa gelatinase;72kDa type IV collagenase);CLG 4;CLG 4A;Collagenase Type 4 alpha;Collagenase type IV A;Gelatinase alpha;Gelatinase neutrophil;Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase;Matrix Metalloproteinase 2;Matrix metalloproteinase 2 (gelatinase A;Matrix metalloproteinase II;MMP 2;MMP II;Neutrophil gelatinase;PEX;TBE 1;MMP-2

Research Areas:Cardiovascular;Cancer;Cell Biology;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:12G7

UNIProt ID:P08253

Accession:

Background:Matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human MMP2 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000;

Calculated MW:74 kDa

ObservedMW:64 kDa