Recombinant MCM5 Monoclonal Antibody

SKU: AN301598L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:MCM5

Target Synonym:MGC;Cell division cycle;DNA replication licensing factor MCM;Minichromosome maintenance complex component;P1-CDC;P1 CDC;CDC;MCM;MCM5;CDC46;P1-CDC46;CDC 46;CDC46 homolog;Cell division cycle 46;DNA replication licensing factor;DNA replication licensing factor MCM5;MCM 5;MGC5315;Minichromosome maintenance complex component 5;P1 CDC46;DNA replication licensing factor MCM 5;Minichromosome maintenance complex component 5;Minichromosome maintenance deficient (S. cerevisiae) 5;Minichromosome maintenance deficient 5;Minichromosome maintenance deficient protein 5

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A301

UNIProt ID:P33992

Accession:

Background:Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Interacts with MCMBP.

Concentration:1 mg/mL

Immunogen:Recombinant human MCM5 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100;IF 1:50

Calculated MW:82 kDa

ObservedMW:82 kDa