Recombinant IKB beta Monoclonal Antibody

SKU: AN301851L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:IKB beta

Target Synonym:TRIP;NFKBIB;IKBB;TRIP9;I kappa B beta;IkappaBbeta;I-kappa-B-beta;IKB beta;IkB-B;IkBbeta;IkB-beta;NF kappa BIB;NF-kappa-B inhibitor beta;NF-kappa-BIB;Thyroid receptor interacting protein 9;Thyroid receptor-interacting protein 9;TR interacting protein 9;TR-interacting protein 9;TRIP-9

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IF;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A563

UNIProt ID:Q15653

Accession:

Background:IkB-beta a protein of the NF-kappa-B inhibitor family. IKB beta Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with IKB beta-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Concentration:1 mg/mL

Immunogen:Recombinant human IKB beta fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;FCM 1:50-1:100;IF 1:50-1:100

Calculated MW:60 kDa

ObservedMW:48 kDa