Recombinant Human XPNPEP2 Protein (His Tag)

SKU: PKSH033349

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: XPNPEP2

Target Synonym: Aminoacylproline Aminopeptidase;Membrane-Bound APP;Membrane-Bound AmP;Membrane-Bound Aminopeptidase P;X-Pro Aminopeptidase 2;XPNPEP2;Xaa-Pro Aminopeptidase 2;mAmP

Research Areas: Signal Transduction;Cell biology;Cancer;metabolism;

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: O43895

Accession: O43895

Background: Xaa-Pro aminopeptidase 2 (XPNPEP2) belongs to the peptidase M24B family of metalloproteases. Human XPNPEP2 is widely expressed in various tissues; such as kidney; lung; heart; placenta; liver; small intestine and colon. However; it doesn’t express in brain; skeletal muscle; pancreas; spleen; thymus; prostate; testis and ovary. XPNPEP2 is a Homotrimer which binds 2 manganese ions per subunit. The metalloprotease XPNPEP2 may play a role in the inflammatory process and other reactions produced in response to injury or infection and the metabolism of the vasodilator bradykinin.

Concentration:

Activity: Not validated for activity

Sequence: His22-Ala650

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 71.6 kDa

ObservedMW: 78 kDa